In order to successfully install and use KInNeSS, you need KDE 3.1.x or newer (which requires Qt 3.1.x) and SANNDRA-1.2.0. (which requires standard C++ library and pthread library). KDE 3.2.x is not required, but adds couple of minor features like saving the author's name in the network description. SANNDRA as far as I tested does not compile with gcc older than gcc-3.0 due to multiple levels of templating. I built it with gcc-3.2.2, 3.3.2, and 3.3.4 on both of my systems, now I use 4.0.2 20050901 prerelease (it comes with SuSE-10). You can get latest SANNDRA on the KInNeSS home page. I did not test KInNeSS on systems other than Linux and there might be a problem of multithreading support on other Unices. Please let me know any kind of experience you had with KInNeSS on other platforms.

KInNeSS itself uses about 21 Mb of memory to run, but this can be increased by the size of the models you are building (count 2Kb per compartment).

You can monitor a list of changes in html ChangeLog and general requirements updates on the KInNeSS home page.